On Thu, May 8, 2008 at 10:02 AM, Richard Loosemore <[EMAIL PROTECTED]> wrote: > Anyhow it is very interesting. Perhaps savantism is an attention mechanism > disorder? Like, too much attention.
Yes. "Autism is a devastating neurodevelopmental disorder with a polygenetic predisposition that seems to be triggered by multiple envi ronmental factors during embryonic and/or early postnatal life. While significant advances have been made in identifying the neuronal structures and cells affected, a unifying theory that could explain the manifold autistic symptoms has still not emerged. Based on recent synaptic, cellular, molecular, microcircuit, and behavioral results obtained with the valproic acid (VPA) rat model of autism, we propose here a unifying hypothesis where the core pathology of the autistic brain is hyper-reactivity and hyper-plasticity of local neuronal circuits. Such excessive neuronal processing in circumscribed circuits is suggested to lead to hyper-perception, hyper-attention, and hyper-memory, which may lie at the heart of most autistic symptoms. In this view, the autistic spectrum are disorders of hyper-functionality, which turns debilitating, as opposed to disorders of hypo-functionality, as is often assumed. We discuss how excessive neuronal processing may render the world painfully intense when the neocortex is affected and even aversive when the amygdala is affected, leading to social and environmental withdrawal. Excessive neuronal learning is also hypothesized to rapidly lock down the individual into a small repertoire of secure behavioral routines that are obsessively repeated. We further discuss the key autistic neuropathologies and several of the main theories of autism and re-interpret them in the light of the hypothesized Intense World Syndrome." http://heybryan.org/intense_world_syndrome.html See also the last email I sent out on this subject: http://heybryan.org/pipermail/hplusroadmap/2008-May/000466.html - Bryan ------------------------------------------- agi Archives: http://www.listbox.com/member/archive/303/=now RSS Feed: http://www.listbox.com/member/archive/rss/303/ Modify Your Subscription: http://www.listbox.com/member/?member_id=8660244&id_secret=101455710-f059c4 Powered by Listbox: http://www.listbox.com
