You'd get a hell of a lot better resolution with an e-beam blowing up 
nanometer-sized spots, and feeding the ejecta thru a mass spectrometer.
See my talk a couple of years back at Alcor. But I would suggest that this is 
*waaaay* off-topic for this list... uploading implications to the contrary 
notwithstanding.

On Friday 30 May 2008 04:42:07 pm, Steve Richfield wrote:
> Ben, et al,
> 
> I have posted in the past as part of other postings that live forever
> machines should be at once much easier to build, worth far more than an AGI,
> and lead directly to an AGI. However, no one has even commented on this. If
> I am right, then present efforts should shift in that direction. If I am
> wrong, then efforts directed in that direction should be redirected here.
> Hence, this IS an important issue to consider here.
> 
> Live forever Machine: An assembly line that takes dying/dead people, scans
> out their entire brain structure, and installs that structure into a new
> android body that is both repairable and capable of periodic checkpoints. In
> short, to last forever, potentially outliving even our own sun. Of course,
> additional computing capacity could be installed, thereby making AGIs.
> 
> Note that the main barrier both to AGI and to live forever machines is the
> present inability to easily scan out present brain structure. I have
> explained on other forums how to do this, but it would take some investment
> in new machinery. The missing device is a scanning UV fluorescence
> microscope, which would focus isolated spots of UV a few microns into brain
> tissue and observe the fluorescence and decay characteristics, and then move
> on to other spots until the top few microns were completely scanned out.
> Then, a cryostatic microtome would slice off ~4 microns and the process
> would continue anew, with a computer matching up the newly exposed surface
> with the deeper part of the structure previously scanned out.
> 
> Brain tissue is (nearly) transparent and is richly fluorescent, providing a
> map of chemical structure from its fluorescence. There are experts (like
> Kathryn Graubard) in this area, but all they have to use are non-scanning
> fluorescence microscopes that only have visible-light resolution, no ability
> to read out decay characteristics, and no attached computers to make the
> best of the available information.
> 
> From the physical mapping, the computer would then generate a logical
> mapping, which would then be put into a simulation program to continue the
> operation of the scanned-out brain.
> 
> Presuming that the entire AGI concept is indeed correct, this logical
> mapping could then be added onto, to make an AGI of limitless capability,
> but with the continuing consciousness of a specific individual human. This
> provides a smooth path to an AGI but without having to solve the early
> development puzzles, or having to understand the myriad "little details"
> that doubtless stand in the way of people-programmed efforts. Then, one we
> actually have a functioning AGI whose operations is 100.00% observable, we
> can work on completely understanding it to make better.
> 
> It seems like SUCH a waste of time and effort here to be working on theories
> and ideas, most of which would be made instantly obsolete by the appearance
> of a scanning UV fluorescence microscope. Wouldn't it be MUCH better to
> focus on making at least one of these machines to answer substantially all
> of the outstanding questions regarding how we work?
> 
> Certainly, any potential investor would have to see the need for such a
> device to assure future AGI success (not to mention finding the cures to
> countless diseases), so if there is to be any substantial investment into
> AGI efforts, it would seem reasonable to expect to see the first money going
> into a scanning UV fluorescence microscope.
> 
> *Hence, if YOU are looking for money for AGI development, then you should
> also be looking for money to develop a scanning UV fluorescence microscope,
> as it will insure that you can figure out EVERYTHING needed to make an AGI.
> Otherwise, all you need is just one puzzle that you can't see how to solve,
> and your entire effort ends up in the bit bucket. Your prospective investors
> are probably focuesd on just such problems as you read this. This would not
> only be cheap insurance, but should help your investor(s) see that you
> WILLsucceed, despite any unforeseen problems.
> *
> **
> Not only is AGI stymied by the lack of this device, but so is neuroscience,
> cancer research, and a number of other biological fields. Of course, it
> hasn't occurred to biologists that this device is practical to make because
> they can't see their way past the computer problems - that many of the
> people here on this forum could handle, even with a hangover.
> 
> Steve Richfield
> 
> 
> 
> -------------------------------------------
> agi
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