I would caution people just saying HTM is supported by 'x' papers. As for 
@Zoey_Lee question, it's neural plausible, not necessarily neurally confirmed.

If you don't want to read every one of the cited papers, I think the main take 
away from neuroscience and cortical columns that HTM has clung to as its core 
concept is mostly just the SDR aspect of it. Everything else seems to be made 
to enforce that sparseness. The idea being that if two codes overlap 
significantly enough, then they can be considered the same or similar enough. 
Then essentially what you are doing for sequences is finding the similarity 
between the current state PLUS the previous states compared to the viewed code.

As far as being closely related to biology, I would have to disagree. HTM 
theory does many things that the brain does not do, solely to get the same 
effect as the brain. Like the global and local inhibition functions. The idea 
is that an interneuron plays a role on deciding which of a cluster of neurons 
fires. The first that fires sends a signal to the interneuron and the 
internueron stops the others that are connected to it from firing. What HTM 
does is replicates that sparse functionality by having inhibition radiuses or 
even a global modifier that just lets the top x% fire and all of the others 

So I wouldn't say it is closely based on biology, but it has taken lessons to 
try to replicate similar results that are important in what makes intelligence. 
But in very different ways.

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