Hi Henrik,
  after managing to install and run correctly aroma package, I ran the 
Paired total copy number analysis CRMAv2 (It's the first time, so I 
strictly followed the vignette). At the end when trying to display the 
results

# Link the ChromosomeExplorer to the segmentation model
ce <- ChromosomeExplorer(cns);
print(ce);

# Fit the model for a few chromosomes
process(ce, chromosomes=c(12, 13, 17), verbose=verbose);


R crushed because of the wrong version of Xcode (I have already installed the 
latest one); I tried to look for the cbs final report in my working directory, 
but I wasn't able to find it.


Do I have to run again all the code and add a particular command at the end for 
saving the output, or is it just that it has been saved somewhere else?


Thank you very much for your patience!


Martina



Il giorno lunedì 24 settembre 2012 19:55:51 UTC+2, Henrik Bengtsson ha 
scritto:
>
> On Mon, Sep 24, 2012 at 5:55 AM, tClaus Lindbjerg Andersen 
> <clausli...@gmail.com <javascript:>> wrote: 
> > Hi, 
> > 
> > Last week I ran CRMA (v2): Paired total copy number analysis 
> > 
> > Using the following annotation files 
> > 
> > GenomeWideSNP_6,Full,na31,hg19,HB20110328.ugp 
> > 
> > GenomeWideSNP_6,Full,na31,hg19,HB20110328.ufl 
> > 
> > GenomeWideSNP_6,Full,monocell.CDF 
> > 
> > GenomeWideSNP_6,HB20080710.acs 
> > 
> > The script ran without any problems. 
> > But I am a little uncertain about whether the output is mapped to hg18 
> or 
> > hg19 ? 
> > 
> > As the annotation files are hg19 I expected the output to be so, too. 
> > But in the outfile from CBS "regions.xls" all entries are associated url 
> of 
> > this format 
> > 
> http://genome.ucsc.edu/cgi-bin/hgTracks?clade=vertebrate&org=Human&db=hg18&position=chr1%3A32255-386024
>  
> > 
> > Indicating that the mapping is to hg18.....? 
> > Can anyone explain ? 
>
> Don't worry, everything in your analysis is correct.  It's just that 
> the file generated by CbsModel has "hg18" hard wired in the output. 
> You can manually search-and-replace "hg18" and "hg19" and everything 
> should be as you expected. 
>
> /Henrik 
>
> > 
> > Help will be much appreciated !! 
> > 
> > Claus 
> > 
> > -- 
> > When reporting problems on aroma.affymetrix, make sure 1) to run the 
> latest 
> > version of the package, 2) to report the output of sessionInfo() and 
> > traceback(), and 3) to post a complete code example. 
> > 
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-- 
When reporting problems on aroma.affymetrix, make sure 1) to run the latest 
version of the package, 2) to report the output of sessionInfo() and 
traceback(), and 3) to post a complete code example.


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