| Hi, if you're annotating multiple sequences that are similar, you should look at our program: Genome Annotation Transfer Utility (GATU) annotates a genome based on a very closely related reference genome. The proteins/mature peptides of the reference genome are BLASTed against the genome to be annotated in order to find the genes/mature peptides in the genome to be annotated. Tcherepanov VT, Ehlers A, Upton C. (2006) Genome Annotation Transfer Utility (GATU): Rapid annotation of viral genomes using a closely related reference genome. BMC Genomics. 2006 Jun 13;7(1):150 It can take 90% of the drudgery out of annotation. And it writes a GenBank file at the end. Cheers, Chris On Oct 23, 2006, at 1:31 AM, Tim Carver wrote: Hi Jay Chris Upton Ph.D. Associate Professor Biochemistry and Microbiology Tel. 250-721-6507 University of Victoria Fax 250-721-8855 P.O. Box 3055 STN CSC Victoria, BC V8W 3P6 Canada
web.uvic.ca/~cupton www.virology.ca www.biodirectory.com/uptons_blog.html
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