I've used Free Download Manager for many years, and it is fully accessible with both JAWS and NVDA.
When you open FDM, it will take you to the download's list, where everything that you've downloaded should be viewed easily. If you have no downloads, then the window should normally be blank. Press alt and there you ought to be able to open the file menu, edit menu, and so on.
Free Download Manager comes even with keyboard shortcuts, so not sure why you are encountering this problem.
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