Thank you for this explanation. It is very helpful.

Best,
MaryAnn

On Tue, Jul 2, 2019 at 5:35 AM Tomas Leal <[email protected]> wrote:

> The XX configuration is tricky, which many either forget or do not
> realize. The Y-gene is so easy to follow because it always comes directly
> from father to son, father to son, at so on. My Y-gene is the exact same
> one my several times great-grandfather had (unless some genetic mutation
> occurred in between).
>
> With a female child, each parent contributes an X gene. Which grandmother
> that particular X gene came from is another matter.
>
> The X gene passed father to daughter had to come from the father's mother;
> however, she had an X gene from each parent, so the X gene the father
> passed on could have come either from his mother's mother or his mother's
> father. In turn, that X gene could have come from different grandmothers.
>
> What this means is full sisters can have different X genes via their
> mother, as the one from their mother passed could have come from any one of
> three grandmothers (either of two passed from the mother's parents or  one
> passed by the father)! Add in great-grandmothers and it's even more
> complicated.
>
> In the case presented here, the fathers were different so the X gene each
> one passed could be from a different grandmother as well. Thus, we can see
> the importance of "triangulation" of getting DNA samples from first cousins
> for comparisons, in addition to that from siblings.
>
> Tomás Leal
>
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