aus "Nature Clinical Practice Endocrinology & Metabolism (2008) 4, 303-304"
Ceelen et al. retrospectively investigated whether children conceived following in vitro fertilization (IVF) were at increased risk of developing cardiometabolic problems. The researchers compared 225 children born after IVF with a control group of 225 spontaneously conceived children matched for age and sex. All children (mean age at the time of follow-up 12.3 years, range 8–18 years) were born to parents with suboptimal fertility. All participants' blood pressure, skinfold thickness and body weight and height were recorded. A subset of 131 pubertal children from each group provided blood samples for measurement of indicators of insulin resistance. Systolic and diastolic blood pressures, the sum of skin-fold thicknesses and fasting glucose levels were all significantly higher in children conceived following IVF than in controls. No significant differences were found between the two groups in fasting insulin concentrations, insulin resistance, or height and weight measurements. Multivariate regression analysis showed that blood pressure and fasting glucose levels remained significantly increased in IVF-conceived children after controlling for confounding factors. -- Der GMX SmartSurfer hilft bis zu 70% Ihrer Onlinekosten zu sparen! Ideal für Modem und ISDN: http://www.gmx.net/de/go/smartsurfer
