The study of the human genome is slowly moving from the area of professionals to a point where it's available to amateurs. <https://www.23andme.com/>23andMe offers a commericial service to compare your genes with friends, family and the world and decipher the history written in your genes (<https://www.23andme.com/store/>starting at 999 US$). <http://mydaughtersdna.org/>MyDaughtersDNA.org takes a different approach in their community focused on aiding those with challenging genetic conditions. Non-commericial in nature, it is a forum dedicated to expanding the understanding of genetics conditions and variations in the human genome, motivated by a personal cause: The inspiration for this site comes from the unusual coincidence that I was trained as a clinical geneticist and I have a <http://mydaughtersdna.org/Members/hyrjr/my-daughter>daughter with an unknown genetic syndrome. The community of clinical geneticists have been diligent and helpful but a definitive diagnosis remains elusive. It is very possible she has a new syndrome but despite my efforts, the molecular (or DNA) variant causing the syndrome is not known with certainty though I have identified a <http://mydaughtersdna.org/Members/hyrjr/the-reasoning-behind-the-dna-analysis>candidate. Were I not a physician trained as a geneticist, it is likely my daughter’s condition would be lumped together with other patients in a category of heterogeneous but similar clinical conditions. This is the standard and respectable way that physicians deal with novelty. It is a way station on the path to some greater understanding of human biology. It takes the trained eye to spot the uniqueness of a case, sometimes a lucky scientific insight, or simply the tincture of time for science to catch up with the human condition. In all cases, the question at hand -- what does she have -- has to be asked and re-asked and that is best done of everyone. This site allows that open question to hang out in the public begging unapologetically for an answer.

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Posted By johl to <http://www.monochrom.at/english/2008/08/personal-genetics.htm>monochrom at 8/06/2008 11:33:00 AM

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