I am looking for a database solution for the microarray facility at  
Fred Hutchinson Cancer Center. We are a core facility with dozens of  
users from labs around the Center and outside. I am looking carefully  
at BASE, TM4, Longhorn, and maxdLoad2. I have a few questions about  
BASE that would help me make this decision. Any feedback would be  
very much appreciated.

Is BASE support for PostgreSQL as strong as support for MySQL?

Can I get a detailed version of the schema? All I can find is a  
general schema overview with tables listed but no  fields. The html  
version of the schema description http:// 
opensource.microarray.omrf.org/wiki/bin/view/BASE/DatabaseSchema is  
apparently cut off or just was never finished.

Are there tools for batch upload of data?  Particularly, I am looking  
at the situation where our users have designed an experiment, and  
hybridizations, we (the core lab) will perform the hybridization,  
scan the array, run a spot analysis (GenPix) upload the data  
(hopefully not using a web based interface one image at a time). We  
will then perform standard normalizations / filters and need to get  
all this into the database so that our users can analyze the data  
later. I this a situation that BASE would be strong at?

When will BASE 2.0 be ready for production?

How many labs are currently using BASE?

If you have any ideas about how the various alternatives stack up  
please let me know. Be as technical as needed, I am an experienced  
programmer and with lots of database experience.

Is there support for HUGE datasets like Tiling arrays? In these cases  
we would not necessarily want to hold all of the results as  
individual records but rather would want to hold the .cel files in  
some structure so that our users could get to them for analysis using  
other tools.

Thanks

David




David Waring Ph.D.
Programmer, Genomics Resource
Fred Hutchinson Cancer Research Center
[EMAIL PROTECTED]





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