Diesel Exhaust May Impair Blood Vessel Function
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USA: December 21, 2005
 

NEW YORK - Exposure to diesel exhaust fumes appears to interfere with the
normal functioning of the body's blood vessels, European investigators
report. "These important findings," they say, provide a potential
mechanism that links air pollution to the development of blood clots and
heart attack. 
 

Although the harmful effects of air pollution on cardiovascular illness
and death are well recognized, the mechanisms involved have been unclear.

Dr. Nicholas L. Mills, from the University of Edinburgh in the UK, and
colleagues evaluated vascular function in 30 healthy volunteers after
they exercised on a stationary bicycle for 1 hour during exposure to
fumes from an idling diesel engine. The particulate concentration was
maintained at a level encountered in the urban environment. The results
were compared with those obtained after breathing normal filtered air. 

According to a report in the medical journal Circulation, the expected
increase in blood flow in the forearm in response to infused agents that
dilate blood vessels was significantly blunted after exposure to diesel
exhaust fumes but not after exposure to normal air. 

Reduced blood flow could fuel blood clots "that could plausibly result in
acute cardiovascular events," Mills and colleagues theorize. 

Mills suggests in a press statement that retrofit devices that trap
diesel exhaust particles might "reduce pollution exposure and benefit
public health." 

SOURCE: Circulation December 20, 2005. 
http://www.planetark.com/dailynewsstory.cfm/newsid/34151/story.htm
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