On 07/29/2013 12:00 AM, Dario Strbenac wrote:
Because I only allowed unique mappings, the ratio is 2. After installing the 
development package versions, I only got a 10% improvement.

Mmmh that's disappointing. Can you put the file somewhere so I can have
a look? Thanks.

H.


    user  system elapsed
1681.36   65.79 1752.10

________________________________________
From: Pages, Herve [hpa...@fhcrc.org]
Sent: Monday, 29 July 2013 3:29 PM
To: Dario Strbenac
Cc: bioc-devel@r-project.org
Subject: Re: [Bioc-devel] Running Time of readBamGappedAlignmentPairs

Hi Dario,

The function was optimized in Bioc-devel. Depending on the number
of records in your BAM file (which is more relevant than its size),
it should now be between 2x and 5x faster. Please give it a try and
let us know.

Also keep in mind that the pairing algo will slow down if
the "average nb of records per unique QNAME" is 3 or more.
This was discussed here last month:
   https://stat.ethz.ch/pipermail/bioconductor/2013-June/053390.html

Cheers,
H.


----- Original Message -----
From: "Dario Strbenac" <dstr7...@uni.sydney.edu.au>
To: bioc-devel@r-project.org
Sent: Sunday, July 28, 2013 9:00:30 PM
Subject: [Bioc-devel] Running Time of readBamGappedAlignmentPairs

Hello,

Could readBamGappedAlignmentPairs be optimised ? It's surprising that it takes 
an extra 29 minutes to calculate the pairing information, for the example 
below. The BAM file is 4 GB in size.

system.time(RNAreads <- readBamGappedAlignmentPairs(file))
    user  system elapsed
1852.16   59.00 1939.11
system.time(RNAreads <- readBamGappedAlignments(file))
    user  system elapsed
  192.80    8.12  214.97

--------------------------------------
Dario Strbenac
PhD Student
University of Sydney
Camperdown NSW 2050
Australia

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--
Hervé Pagès

Program in Computational Biology
Division of Public Health Sciences
Fred Hutchinson Cancer Research Center
1100 Fairview Ave. N, M1-B514
P.O. Box 19024
Seattle, WA 98109-1024

E-mail: hpa...@fhcrc.org
Phone:  (206) 667-5791
Fax:    (206) 667-1319

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