A colleague and I are designing a package for quantitative proteomics data, and 
we are debating whether to base it on the SummarizedExperiment or the 
ExpressionSet class. 

There is no immediate use for the ranges aspect of SummarizedExperiment, so 
that would have to be carried around with NAs, and this is a parsimony argument 
for using ExpressionSet instead. OTOH, the interface of SummarizedExperiment is 
cleaner, its code more modern and more likely to be updated, and users of the 
Bioconductor project are likely to benefit from having to deal with a single 
interface that works the same or similarly across packages, rather than a 
variety of formats; which argues that new packages should converge towards 
SummarizedExperiment(’s interface).

Are there any pertinent insights from this group?

Thanks and best wishes
Wolfgang

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