Hi,

The file is downloaded and filtered from the ilincs website. Unfortunately
it is not readily available from ilincs.org itself. We have the capability
of storing the file in our S3 buckets, however.

The metadata under discussion is metadata related to each individual
signature stored in iLINCS, including information about the cell lines, the
time points and the dosages. From what I understand this is more likely to
be suited for ExperimentHub since it's processed.


Regards,
Dr. Ali Sajid Imami
LinkedIn <https://pk.linkedin.com/pub/ali-sajid-imami/50/956/2a6>


On Thu, Aug 31, 2023 at 12:02 PM Kern, Lori via Bioc-devel <
bioc-devel@r-project.org> wrote:

> Hello,
>
> Regarding Hub use:
> What sort of information does the metadata contain? That would determine
> whether ExperimentHub or AnnotationHub is more appropriate. Is the file
> accessed directly from the http://ilincs.org/ portal with a url link or
> is there processing/filtering that occurs?  The hubs can access data stored
> on other websites/hosts as long as they are trusted sites (ilincs would
> fall in this category) if you can access it directly with a url link.  The
> way the hubs work is the data is stored elsewhere either directly from site
> access or on some hosting serve (S3, Azure, etc) if its processed. The data
> would be removed from directly being in the package, and downloaded then
> using the hub interface when needed (and also cached in the backend so its
> not done every time).
>
>
>
>
>
> Lori Shepherd - Kern
>
> Bioconductor Core Team
>
> Roswell Park Comprehensive Cancer Center
>
> Department of Biostatistics & Bioinformatics
>
> Elm & Carlton Streets
>
> Buffalo, New York 14263
>
> ________________________________
> From: Bioc-devel <bioc-devel-boun...@r-project.org> on behalf of Vincent
> Carey <st...@channing.harvard.edu>
> Sent: Thursday, August 31, 2023 8:29 AM
> To: Martin Grigorov <martin.grigo...@gmail.com>
> Cc: bioc-devel@r-project.org <bioc-devel@r-project.org>
> Subject: Re: [Bioc-devel] Including large files for the package
>
> On Thu, Aug 31, 2023 at 7:28 AM Martin Grigorov <martin.grigo...@gmail.com
> >
> wrote:
>
> > Hello,
> >
> > Perhaps you could use
> https://secure-web.cisco.com/1PWeIBsHtYFpwnIBjpsq_YN8z0VkqqbOqtHQk4ITS1RC58_4Mploz6OJS4-Uxw4jq_g9JHqlT9Wq6tkKR-aBwYiSF6Bf-ajT-d7vnHBJlAHNLxs2Y3F979xVFa07xAiyrpeXtgfU0dHry6aNaTQmruT5HzYIplDg0UVfcLK9976qFmnnwuRbo24PxtCSMLTLKbVqlHi_URSb7MYdKpuxIP8SmFalHHQUUZWSG9NT1XSeuTkw8pXPtGzJPB2vyj-zO3-cy9RUHz5gLoFe53a3qV2cRVz7ov7WXhLErjX9fqk7A-EQOQSq5QeyWzmoonEUu/https%3A%2F%2Fbioconductor.r-universe.dev%2FBiocFileCache
> to
> > download the big file on demand.
> > The benefit is that the file would be stored in ~/.cache/R/yourPackage/
> > (for Linux; something similar for Windows/Mac) and reused between
> sessions.
> >
>
> Thanks Martin.  I think that is a possible approach, but the proposals at
>
> http://secure-web.cisco.com/1PN99uHlZGkagOQGmEM4lhVob-mny_wuOMrU_eG-JFkBnBX5W-tXbKupcTbZ-gSq-XMcO9_rg2sGp_3KwriGP5nkPGjk_bL8O5IxcEaPE04uFIvB_UVQh-2NzX-1LfalQo2nPrpuxM3FDJJJPRBz8pjayIb27ThNpZZQI50lyjOLdJUikYdS5-Y4TlTMDGCPfs_854qpfJREWoKeYTJOpRb-95SzxaPxDp2qePIkigSmQzj1JrjIfCYyLGCVIIq1Zz1-kbIEqem7cvMtWe2ZE_Af1yG9wA-51shDuYxapn9yaETK7E8Rsg_OTsp4yfB-R/http%3A%2F%2Fcontributions.bioconductor.org%2Fnon-software.html%3Fq%3DAnnotationHub%23annotationexperiment-hub-packages
> should also be considered.
>
> Ali, if the documentation regarding *Hub contributions is unclear, please
> file an
> issue or write back here with the difficulties so that we can improve the
> material and
> the methods!
>
> Thanks!
>
>
>
> >
> > Regards,
> > Martin
> >
> > On Tue, Aug 29, 2023 at 5:15 AM Ali Sajid Imami <
> ali.sajid.im...@gmail.com
> > >
> > wrote:
> >
> > > Hi BioConductor Team,
> > >
> > > I am a PhD Candidate in the Cognitive Disorders Research lab at the
> > > university of Toledo. I am responsible for a number of R packages and
> our
> > > intention is to submit them to bioconductor over the next several
> > months. I
> > > had just submitted a package drugfindR (
> > >
> https://secure-web.cisco.com/1cicrzPanVq35q1BPuFjU_LiICsEK7iZoXLM-t2R1mHcgZYx9SUW2VsKWpSf18Qth0RFcer0FVZwPETWM2KmL8gNtvqOXoL4pEnpyzZqLv1acHN06QD6rwkShy1iEZsPyZLIJHhtNgsJEt7_0s7gYZE98GqoE2RSVyYhNOPS_2ZakwjaFtb-w3_dJGmt7wV1GXpapSa6w5gLICAPUjaaw1jFLsgCc_2dCVuc0mX9VGYNJywp_SDKJH8ex4KX6Groq7ThXm-EQbmSxB8WVqCR0rb-vIqAyS2IC_suOg22e6PkjRwYqgwjtN4mf7i6xe7r2/https%3A%2F%2Fgithub.com%2FCogDisResLab%2FdrugfindR).
> This was immediately closed
> > as
> > > my repo had a single file over the 5MB limit.
> > >
> > > I wanted to ask both if you would reconsider/make an exception or guide
> > me
> > > in the right direction.
> > >
> > > This package serves as a way to quickly learch through the LINCS data
> > > stored at the ilincs.org portal. The file in question is one of three
> > > metadata files that allows the package to function efficiently and
> > without
> > > having to go through the expensive network requests. It would really be
> > > helpful if we could include the file as is. I do not expect more files
> > like
> > > that to be added to the package at all.
> > >
> > > Barring that, I have seen the suggestion of using AnnotationHub or
> > > ExperimentHub. While I have gone through the documentation, I'm not
> > > entirely sure how those services work. Are those services where we can
> > > store the data itself or we are expected to host the data elsewhere and
> > > create lightweight "pointer" packages. Similarly, I'm not entirely sure
> > > which Hub this would go to.
> > >
> > > Any advice or guidance will be appreciated.
> > >
> > >
> > > Regards,
> > > Dr. Ali Sajid Imami
> > > LinkedIn <
> https://secure-web.cisco.com/1BTO_aZ7cH_8TaD11HyS10Fduxb3co4BqlJudIfzXykrcywobw2n0xsaOdEHdvKApkBAn1ZVq-dlLlBONRSk8O2_5L_2haztYIrFMPYFfQChfhTRe52Gdcvaf0lT4FPdRCC_JHpSCVynfXzds9EeIrf7CriylS-Hs59XtvvUZCfme16xvyeOjQgcY8rV_ODwI6TRsELOKgn34D-kyeRmOmAgaK36NoIFnfZ6uC2BufvWY5TsAXS7hD036WGkg8HSeW2GAYCpYrP95GhfcepkC45lkNsGGRLLFbS58VKw4kdp9OB5XG-9YYJC34SM_5vlF/https%3A%2F%2Fpk.linkedin.com%2Fpub%2Fali-sajid-imami%2F50%2F956%2F2a6
> >
> > >
> > >         [[alternative HTML version deleted]]
> > >
> > > _______________________________________________
> > > Bioc-devel@r-project.org mailing list
> > >
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> >
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> >
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