Ah, thank you very much, sorry for having overlooked this! Yes, that seems the 
source of the problem. Hervé, should I wait for your update or rather change 
the package myself? The latter won’t be a problem for me. I suppose it is just 
about adding ‘pwalign’ as an additional dependency, right?

Thanks and best regards,
Ulrich


From: Martin Grigorov <martin.grigo...@gmail.com> 
Sent: Thursday, April 25, 2024 7:52 AM
To: ulr...@bodenhofer.com
Cc: bioc-devel@r-project.org
Subject: Re: [Bioc-devel] Biostrings: substitution matrices disappeared?

Hi,

Yesterday there was another email about Biostrings - 
https://stat.ethz.ch/pipermail/bioc-devel/2024-April/020395.html
I thought it might be related to your problem.

Regards,
Martin

On Thu, Apr 25, 2024 at 8:23 AM Ulrich Bodenhofer 
<mailto:ulrich.bodenho...@gmail.com> wrote:
Dear colleagues, dear BioC core team,

One of my packages in the devel branch, the ‘msa’ package seems broken since
yesterday. The vignette does not run anymore (therefore, the package does
not build), and the reason is that the BLOSUM62 substitution matrix cannot
be loaded form the ‘Biostrings’ package anymore. I checked the ‘Biostrings’
package. In Version 2.70.3 in the release branch, the substitution matrices
were still in the ‘data/’ directory. In the current devel version 2.71.6,
they have disappeared. I found no hint to that in the NEWS file. So, I want
to kindly ask the maintainers of the ‘Biostrings’ package to give me some
advice how to fix that on my side or, in case that this is an error in the
current devel version of the ‘Biostrings’ package, to have a look into this.

Thanks a lot in advance, best regards,
Ulrich

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