Yes, us too. Users are reporting DESeq2 1.48.0 for Bioconductor 3.21 is failing with something similar:
``` Error in validObject(.Object) : invalid class “DESeqDataSet” object: superclass "ExpData" not defined in the environment of the object's class ``` _______________________________________________ Bioc-devel@r-project.org mailing list https://stat.ethz.ch/mailman/listinfo/bioc-devel
