thanks, this is what I had when the environment variable was still set;

$ R CMD env | grep LD_LIBRARY_PATH
LD_LIBRARY_PATH=/opt/R/R-2.11.0/lib64/R/lib:/usr/local/lib64:/usr/lib64/gcj-4.1.2:/opt/staden-linux-x86_64-1-7-1b/lib/linux-x86_64-binaries


Marcus



On Thu, Jun 3, 2010 at 12:41 PM, Martin Morgan <[email protected]> wrote:

> On 06/02/2010 05:05 PM, Marcus Davy wrote:
> > Hi Martin,
> > I had the same issue only yesterday installing ShortRead on a R-2.11.0
> fresh
> > source installation for redhat enterprise linux with
> > '--prefix=/opt/R/R-2.11.0.' The dependancy Rsamtools failed using
> > biocLite("ShortRead")
> >
> > ** testing if installed package can be loaded
> > Error in dyn.load(file, DLLpath = DLLpath, ...) :
> >   unable to load shared library
> > '/opt/R/R-2.11.0/lib64/R/library/Rsamtools/libs/Rsamtools.so':
> >   /opt/R/R-2.11.0/lib64/R/library/Rsamtools/libs/Rsamtools.so: undefined
> > symbol: deflateSetHeader
> > ERROR: loading failed
> > * removing ‘/opt/R/R-2.11.0/lib64/R/library/Rsamtools’
> >
> > I also traced this to libz.so.1, in this case it was incorrectly pointing
> to
> > an installation of staden on the machine, which I traced by also
> attempting
> > a manual install;
> >
> > ldd /tmp/Rsamtools/src/Rsamtools.so
> > libz.so.1 =>
> > /opt/staden-linux-x86_64-1-7-1b/lib/linux-x86_64-binaries/libz.so.1
> > (0x00002acd7097d000)
> > ...
> >
> > locate libz.so.1
> > /opt/staden-linux-x86_64-1-7-1b/lib/linux-x86_64-binaries/libz.so.1
> > /opt/staden-linux-x86_64-1-7-1b/lib/linux-x86_64-binaries/libz.so.1.2.2
> > /usr/lib/libz.so.1
> > /usr/lib/libz.so.1.2.3
> > /usr/lib64/libz.so.1
> > /usr/lib64/libz.so.1.2.3
> >
> > The environment variable LD_LIBRARY_PATH was being set to
> >
> > /opt/staden-linux-x86_64-1-7-1b/lib/linux-x86_64-binaries
> >
> > What seemed to be happening was the R ./configure was picking up the
> > LD_LIBRARY_PATH to staden (e.g. in ./configure log:  PATH:
> > /opt/staden-linux-x86_64-1-7-1b/linux-x86_64-bin), so I unset the
> > environment variable reinstalled R, then installed ShortRead using
> biocLite
> > without problems
>
> Thanks Marcus -- this helps to clarify -- an incomplete rather than
> non-existent libz; the configure script in Rsamtools looks for a
> particular function that I thought was relatively diagnostic of a modern
> libz, so definitely this allows Rsamtools to get past configure before
> breaking.
>
> A couple of linux / R tricks. Preceding commands with 'R CMD' sets up
> the environment to be the way R sees it, so
>
>  R CMD env | grep LD_LIBRARY_PATH
>
> might differ from env |grep LD_LIBRARY_PATH, and likewise for ldd; this
> can be helpful to distinguish between 'my system is kind of funky' from
> 'my R is kind of funky'. It's also helpful in general, e.g., R CMD
> Sweave someFile.Rnw sets the R environment so that Sweave.sty (in the R
> distribution) is found.
>
> Also, R reads variables from R_HOME/etc/Makevars, and you can override
> settings there with values in ~/.R/Makevars. This makes it cheaper to
> experiment, e.g., with CFLAGS or LD_LIBRARY_PATH, and also to see what
> value LD_LIBRARY_PATH took when R was configured (in R_HOME/etc/Makevars).
>
> Martin
>
> >
> >
> > Cheers,
> >
> > Marcus
> >
> >> version               _
> > platform       x86_64-unknown-linux-gnu
> > arch           x86_64
> > os             linux-gnu
> > system         x86_64, linux-gnu
> > status
> > major          2
> > minor          11.0
> > year           2010
> > month          04
> > day            22
> > svn rev        51801
> > language       R
> > version.string R version 2.11.0 (2010-04-22)
> >
> >
> > On Thu, Jun 3, 2010 at 6:13 AM, Martin Morgan <[email protected]>
> wrote:
> >
> >> Hi Kanika --
> >>
> >> On 06/02/2010 05:48 AM, kanika arora wrote:
> >>> Hi ALL,
> >>>
> >>> * *
> >>>
> >>> I am trying to install l.0.2 version Rsamtools from Bioconductor and
> >> facing
> >>> problems. Please find the error message mentioned below:
> >>>
> >>>
> >>>
> >>>
> >>>
> >>> ** help
> >>>
> >>> *** installing help indices
> >>>
> >>>   converting help for package âRsamtoolsâ
> >>>
> >>>     finding HTML links ... done
> >>>
> >>>     BamViews-class                          html
> >>>
> >>>     finding level-2 HTML links ... done
> >>>
> >>>
> >>>
> >>>     Rsamtools-package                       html
> >>>
> >>>     ScanBamParam-class                      html
> >>>
> >>>     readBamGappedAlignments                 html
> >>>
> >>> Rd warning: ./man/readBamGappedAlignments.Rd:10: missing file link
> >>> âGappedAlignmentsâ
> >>>
> >>> Rd warning: ./man/readBamGappedAlignments.Rd:36: missing file link
> >>> âGappedAlignmentsâ
> >>>
> >>>     readPileup                              html
> >>>
> >>> Rd warning: ./man/readPileup.Rd:34: missing file link âGRangesâ
> >>>
> >>>     scanBam                                 html
> >>>
> >>> ** building package indices ...
> >>>
> >>> ** testing if installed package can be loaded
> >>>
> >>> Error in dyn.load(file, DLLpath = DLLpath, ...) :
> >>>
> >>>   unable to load shared library
> >>> '/usr/lib64/R/library/Rsamtools/libs/Rsamtools.so':
> >>>
> >>>   /usr/lib64/R/library/Rsamtools/libs/Rsamtools.so: undefined symbol:
> >>> gzopen64
> >>
> >>
> >> Rsamtools depends on having a system 'libz' installed. Does your system
> >> have this (e.g., for me,
> >>
> >> mtmor...@mm:~> /sbin/ldconfig -p|grep libz
> >> [...snip...]
> >>        libz.so.1 (libc6,x86-64) => /lib64/libz.so.1
> >>        libz.so.1 (libc6) => /lib/libz.so.1
> >>        libz.so (libc6,x86-64) => /usr/lib64/libz.so
> >>
> >> This should be checked during package configuration, so I'm a little
> >> surprised that the error comes up at this point. Can you confirm that
> >> you are installing this with
> >>
> >>  biocLite('Rsamtools')
> >>
> >> ? I'm a little nervous that when you say you 'installed all the
> >> dependencies' that you are doing something else -- biocLite('Rsamtools')
> >> installs the correct version of the dependencies for your version of R.
> >>
> >> Martin
> >>
> >>> ERROR: loading failed
> >>>
> >>> * removing â/usr/lib64/R/library/Rsamtoolsâ
> >>>
> >>>
> >>>
> >>>
> >>>
> >>>> sessionInfo()
> >>>
> >>> R version 2.11.0 (2010-04-22)
> >>>
> >>> x86_64-redhat-linux-gnu
> >>>
> >>>
> >>>
> >>> locale:
> >>>
> >>>  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C
> >>>
> >>>  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8
> >>>
> >>>  [5] LC_MONETARY=C              LC_MESSAGES=en_US.UTF-8
> >>>
> >>>  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C
> >>>
> >>>  [9] LC_ADDRESS=C               LC_TELEPHONE=C
> >>>
> >>> [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C
> >>>
> >>>
> >>>
> >>> attached base packages:
> >>>
> >>> [1] stats     graphics  grDevices utils     datasets  methods   base
> >>>
> >>>
> >>>
> >>> other attached packages:
> >>>
> >>> [1] goseq_1.0.1            geneLenDataBase_0.99.4 BiasedUrn_1.03
> >>>
> >>>
> >>>
> >>> loaded via a namespace (and not attached):
> >>>
> >>>  [1] AnnotationDbi_1.10.1 Biobase_2.8.0        Biostrings_2.16.2
> >>>
> >>>  [4] BSgenome_1.16.1      DBI_0.2-5            GenomicRanges_1.0.1
> >>>
> >>>  [7] grid_2.11.0          IRanges_1.6.4        lattice_0.18-5
> >>>
> >>> [10] Matrix_0.999375-38   mgcv_1.6-1           nlme_3.1-96
> >>>
> >>> [13] RCurl_1.4-2          RSQLite_0.9-1        rtracklayer_1.8.1
> >>>
> >>> [16] tools_2.11.0         XML_3.1-0
> >>>
> >>>
> >>>
> >>>
> >>>
> >>> I already installed all the dependencies of the package. Please guide
> me
> >> in
> >>> this context.
> >>>
> >>> Thanks in advance,
> >>>
> >>> Kanika
> >>>
> >>>       [[alternative HTML version deleted]]
> >>>
> >>>
> >>>
> >>>
> >>> _______________________________________________
> >>> Bioc-sig-sequencing mailing list
> >>> [email protected]
> >>> https://stat.ethz.ch/mailman/listinfo/bioc-sig-sequencing
> >>
> >>
> >> --
> >> Martin Morgan
> >> Computational Biology / Fred Hutchinson Cancer Research Center
> >> 1100 Fairview Ave. N.
> >> PO Box 19024 Seattle, WA 98109
> >>
> >> Location: Arnold Building M1 B861
> >> Phone: (206) 667-2793
> >>
> >> _______________________________________________
> >> Bioc-sig-sequencing mailing list
> >> [email protected]
> >> https://stat.ethz.ch/mailman/listinfo/bioc-sig-sequencing
> >>
> >
>
>
> --
> Martin Morgan
> Computational Biology / Fred Hutchinson Cancer Research Center
> 1100 Fairview Ave. N.
> PO Box 19024 Seattle, WA 98109
>
> Location: Arnold Building M1 B861
> Phone: (206) 667-2793
>

        [[alternative HTML version deleted]]

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