Sangamo BioSciences to Present at the BioCentury Future Leaders in 
the Biotech Industry Conference 

RICHMOND, Calif., March 23 /PRNewswire-FirstCall/ -- Sangamo 
BioSciences, Inc. (NASDAQ:SGMO) announced today that it will be 
presenting at the BioCentury and Thomson Financial Future Leaders in 
the Biotech Industry Conference at 10:00 a.m. Eastern Time on 
Thursday, March 30, 2006 at the Millennium Broadway Hotel in New 
York. Edward Lanphier, Sangamo's president and chief executive 
officer, will provide an overview of the company's business strategy 
and an update on the progress of Sangamo's therapeutic development 
programs.


The presentation will be webcast live and may be accessed via a link 
on the Sangamo BioSciences website in the Investor Relations section 
under "Company Overview" http://phx.corporate-ir.net/phoenix.zhtml?
c=0938&p==irol-IRHome . The presentation will be archived on the 
Sangamo website for two weeks after the event.


About Sangamo


Sangamo BioSciences, Inc. is focused on the research and development 
of novel DNA-binding proteins for therapeutic gene regulation and 
modification. The most advanced ZFP Therapeutic(TM) development 
programs are currently in Phase 1 clinical trials for evaluation of 
safety in patients with diabetic neuropathy and peripheral artery 
disease. Other therapeutic development programs are focused on 
macular degeneration, ischemic heart disease, congestive heart 
failure, neuropathic pain, and infectious and monogenic diseases. 
Sangamo's core competencies enable the engineering of a class of DNA-
binding proteins known as zinc finger DNA-binding proteins (ZFPs). 
By engineering ZFPs that recognize a specific DNA sequence Sangamo 
has created ZFP transcription factors (ZFP TFTM) that can control 
gene expression and, consequently, cell function. Sangamo is also 
developing sequence-specific ZFP Nucleases (ZFNTM) for therapeutic 
gene modification as a treatment for a variety of monogenic 
diseases, such as sickle cell anemia, and for infectious diseases, 
such as HIV. Sangamo has established several Enabling Technology 
Agreements with companies to apply its ZFP Technology to enhance the 
production of protein pharmaceuticals. For more information about 
Sangamo, visit the company's web site at www.sangamo.com.


This press release may contain forward-looking statements based on 
Sangamo's current expectations. These forward-looking statements 
include, without limitation, references to the research and 
development of novel ZFP TFs and ZFNs, applications of Sangamo's ZFP 
TF technology platform and clinical trials of ZFP Therapeutics. 
Actual results may differ materially from these forward-looking 
statements due to a number of factors, including technological 
challenges, uncertainties relating to the initiation and completion 
of stages of the ZFP Therapeutic clinical trials, Sangamo's ability 
to develop commercially viable products and technological 
developments by our competitors. See the company's SEC filings, and 
in particular, the risk factors described in the company's Annual 
Report on Form 10-K and its most recent 10-Q. Sangamo BioSciences, 
Inc. assumes no obligation to update the forward-looking information 
contained in this press release. 


Source: Sangamo BioSciences, Inc.

CONTACT: Elizabeth Wolffe, Ph.D., Sangamo BioSciences, Inc.,
+1-510-970-6000, ext. 271, [EMAIL PROTECTED]; or Media, Justin 
Jackson,
+1-212-213-0006, [EMAIL PROTECTED], for Sangamo BioSciences, Inc.


Web site: http://www.sangamo.com/ 



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