http://www.sfgate.com/cgi-bin/article.cgi?file=/news/archive/2003/02/23/fina
ncial0140EST0115.DTL

An experimental AIDS vaccine being developed by VaxGen Inc. does not appear
to protect most people from the disease, but showed promise in protecting
blacks and Asians, the company said late Sunday.

The company's much-anticipated vaccine only reduced the expected rate of
infection by 3.8 percent in the high-risk people who volunteered to take the
treatment. But the expected infection rate for the 314 black volunteers who
received the vaccine was reduced by 78 percent. The rate was reduced by 67
percent for all nonwhite volunteers other than Hispanics.

"This is the first time we have specific numbers to suggest that a vaccine
has prevented HIV infection in humans," VaxGen vice president Phillip Berman
said in a prepared statement Sunday night. "We're not sure yet why certain
groups have a better immune response."

The Brisbane, Calif.-based company said it planned to continue developing
the vaccine and will examine more closely why it worked better in blacks and
Asians than it did in whites and Hispanics.

The publicly traded company's stock has risen and fallen dramatically during
the last year as rumors of the experiment's results swirled. It sold for as
low as $4.81 a share and as high as $23.25. It closed at $13.02 in trading
on the Nasdaq Stock Market Friday.

The experiment, which initially involved 5,400 people at high-risk for the
disease, had been criticized by some activists who say it could encourage
risky behavior. Even if the vaccine proved effective on some level, there
might be no way to tell if it has worked on a particular individual.

But VaxGen has won widespread praise from doctors and the FDA for its
handling of an ethically difficult test. The company counseled patients in
the experiments to practice safe sex because the vaccine may not work and
because one-third of the volunteers received the placebo.

Experts believe a vaccine is the only way to stop the worldwide AIDS
epidemic, which has already killed 20 million people and infected 40 million
more.




xponent
Effort Maru
rob
Realising a form out of stone
Set hands moving
Roan shaped his heart
Thru his working hands
Work to mould his passion into clay
   Like the sun




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