--- The Fool <[EMAIL PROTECTED]> wrote:
>
http://www.cnn.com/2003/HEALTH/conditions/06/04/cancer.nightshifts.reut/
> 
> Nurses who work regular night shifts have a higher
> risk of colon cancer,
> a study found, suggesting a relationship between the
> amount of sunlight exposure and the cancer. 
> 
> The study by researchers at Harvard Medical School
> and Brigham and
> Women's Hospital in Boston supports earlier research
> that found women who
> work night shifts have a higher risk of breast
> cancer.
> 
> "Because night-shift work has become very common in
> developed countries,
> future studies should assess the relationship of
> light exposure to the
> risk of other cancers and consider the risks in
> men," they wrote...

It probably isn't so much the lack of sunlight as it
is the excess of artificial light, which decreases the
~1AM production of melatonin (although lack of
sustained bright light is connected to depression and
I think some other neurochemical problems).

http://my.webmd.com/content/Article/66/79657.htm?printing=true
"...During the dark nighttime hours, the body produces
a hormone called melatonin, "which is also called the
hormone of the dark," Schernhammer says. "The peak
production of melatonin occurs at about 1 or 2 a.m."
Exposure to light at night stops the production of
melatonin. 

"In animal experiments and in some laboratory studies,
melatonin demonstrated the ability to protect against
the development of cancers, and several researchers
suggest that it works the same way in humans, says
Schernhammer..." 

There has also been research suggesting that too much
light at night causes retinal damage (the level was
roughly 'if you can read by it, it's too bright').

I wonder if taking supplemental melatonin (at the
person's 'bedtime') would correct the deficit?  And
since we know that melatonin production decreases with
age (that's why, as a sleeping aid, 1 mg tends to work
better for older folk; I tried it when I was doing
shift work in residency, but it didn't seem to help my
sleep at all), is it a factor in cancer occurence?

And what about those of us who keep bizarre hours
anyway; will our cancer risk be higher?  Hmm, better
keep those multivitamins and fresh veggies coming...

Debbi
whose own sleep cycle used to be 1 or 2AM to 10AM, but
having had to adapt, it's now just non-regular  :P

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