--- Alberto Monteiro <[EMAIL PROTECTED]> wrote:

> And now for something completely different: those
> _vampires_
> that control medical research are not interested in
> finding cures
> for any disease, they are just pumping money into
> expensive
> drugs that make _any_ disease a cronical disease.

This explains why Bayer invested hundreds of millions
to develop cipro, I guess.  While there are certainly
financial incentives that lead them to prefer making
things into chronic diseases, they end up with chronic
diseases because the science goes that way.  I'm
curious, actually, as to what disease exactly you're
referring to.  AIDS?  You go ahead and cure AIDS,
then, Alberto, and then come back to me and tell me
how the "vampire" pharmacos didn't do anything to cure
it, if it's so easy.  Meanwhile, I'll be thankful for
the fact that those "vampires", to little thanks and
less profit, invested billions of dollars of money and
countless hours of time from some of the finest
doctors in the world to change AIDS into a disease
where, if you get it in the West, the odds are you
will die of something else.  That's one of the most
remarkable achievements in medical history.

As a purely rational advisor to the industry, I would
tell them it was the dumbest mistake they ever made,
though.  Any pharmaco that invested in AIDS research
and got a success out of it got _screwed_.  I would
use a harsher word, but I know how it bothers John. 
They took enormous publicity hits, and then were
forced to sell it at a very low price.  From a
business standpoint, any pharmaco that invested in
AIDS twenty years ago made a mistake.  Any pharmaco
that did it today would have to be run by idiots or
saints, and the reason why is precisely the attitudes
you describe.

> They are more evil than the Cocaine Cartel of
> Medellin: at least
> we can say, in favour of the cocaine barons, that
> those that
> take cocaine are not _forced_ to take it in the
> first place.

You're not _forced by the pharmaco_ to take the drug. 
What they manage to do is spend enormous resources and
time to produce products that, if you take them, will
make your life better.  Let's all circle around and
damn them for that, certainly.
> 
> Medical research should never be allowed to be
> controlled
> by private companies. If there is any reason to
> fight Capitalism
> and sponsor Communism, those Drug Dealers are number
> one in my list.

How many drugs did the Soviet Union invent, again? 
Can you name _even one_?  I'll stack the odds in your
favor and give you every Communist country in the
world - the USSR, China, all of Eastern Europe, and
everyone else combined - and say that all of them
together have done less for drug development than
Merck, all by itself.  You can also add in every drug
developed by J&J, Pfizer, Glaxo, AstraZeneca,
ScheringPlough, Novartis, Aventis, and every single
biotech, just to cap things off.

> > I imagine that history will
> > judge the people who made that happen very harshly
> > indeed, actually. 
> >
> I imagine that History will be amazed at the
> passivity
> of the early XXIers, who allowed the Drug Barons to
> monopolize their lifes forever.
> 
> Alberto Monteiro

Not if historians know anything about the industry. 
Now, odds are they won't.  But if you do, you know
that drug creation is split into two parts - research
and development.  Research consists basically of
finding targets.  It's quite difficult.  Governments
do it quite well, pharmacos have historically done it
well but are having less success at the moment.  The
other part is development.  It's _very_ difficult. 
That is taking the target research has found, crafting
a molecule to address it, running it through clinical
trials, altering the molecule to increase efficacy and
decrease toxicity, running it through clinical trials
again, developing a delivery system to consistently
get it to the appropriate organ, running it through
_more_ clinical trials, finally releasing it to the
public after FDA approval, and then conducting _still
more_ clinical trials to make sure that it's safe for
even the rarest of populations.  Governments can't do
that worth shit.  There's no one outside the industry
who has the skills in pharmacological chemistry (to
pick one skill among many) to do those things.

History will, I think, most likely be amazed at the
foolishness of governments that decided to sacrifice
all future innovation and new drug development in
order to get questionable savings on current products.
 You don't want to pay pharmaco prices?  Fine, but
then you should never take any drug that comes onto
the market after today, no matter what the reason. 
Otherwise you're just a parasite, free riding on the
people who do pay for those drugs to be created.

=====
Gautam Mukunda
[EMAIL PROTECTED]
"Freedom is not free"
http://www.mukunda.blogspot.com


                
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