Are there instructions somewhere for importing from FreeSurfer to Caret 5.4 
somewhere?  The only instructions seem to be fairly old and it looks like 
things have changed a bit since then.

-Eric

-----Original Message-----
From: Donna Dierker [mailto:[EMAIL PROTECTED]
Sent: Tue 6/13/2006 8:36 AM
To: [EMAIL PROTECTED]; Caret, SureFit,and SuMS software users
Subject: Re: [caret-users] Cortical Thickness Measurement
 
Hi Darren,

Sorry to be the bearer of bad news, but no:  Caret/SureFit doesn't 
compute cortical thickness.  For a while, a student was working on it, 
but it never went anywhere.  Occasionally, people mistake our sulcal 
depth measure for cortical thickness, but the two are completely 
different measures.  (See David's PALS paper 
(http://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6WNP-4H4T34K-1-3&_cdi=6968&_user=4275&_orig=browse&_coverDate=11%2F15%2F2005&_sk=999719996&view=c&wchp=dGLbVzb-zSkzk&md5=0920fddff1134928d23f0a23d746935f&ie=/sdarticle.pdf),
 
figure 1, for a description of sulcal depth.)

The only good news I can give those who are interested in cortical 
thickness is that you can import your freesurfer surfaces and thickness 
maps into Caret in a mostly automated way, and generate sulcal depth on 
them, if desired.  You can then register them to the PALS_B12 atlas, 
although this requires drawing our Core6 landmark borders:

http://brainvis.wustl.edu/help/landmarks_core6/landmarks_core6.html

Due to algorithmic differences between Freesurfer's and Caret's 
registration algorithms, seeking a "second opinion" can be useful, 
depending on the nature of your study.  For example, the algorithm that 
best aligns intrasubject anatomy across multiple timepoints may not be 
ideal for finding group anatomical differences.

On 06/12/2006 09:09 PM, Darren Weber wrote:

>-----BEGIN PGP SIGNED MESSAGE-----
>Hash: SHA1
>
>
>Hi,
>
>I have been using FreeSurfer for a while, to obtain cortical thickness
>measures.  Is it now possible to obtain thickness measures with caret?
>
>There is a previous thread from 2003 indicating this feature was on a
>wish-list:
>
>http://brainvis.wustl.edu/pipermail/caret-users/2003-September/000076.html
>
>
>Thanks, Darren
>
>
>- --
>
>Darren L. Weber, Ph.D.
>Postdoctoral Scholar
>
>Dynamic Neuroimaging Laboratory,
>UCSF Department of Radiology,
>185 Berry Street, Suite 350, Box 0946,
>San Francisco, CA 94107, USA.
>
>Tel: +1 415 353-9444
>Fax: +1 415 353-9421
>www: http://dnl.ucsf.edu/users/dweber
>
>"To explicate the uses of the brain seems as difficult
>a task as to paint the soul, of which it is commonly
>said, that it understands all things but itself."
>  Thomas Willis (The Anatomy of the Brain and Nerves, 1664)
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>caret-users@brainvis.wustl.edu
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>
>  
>


-- 
Donna L. Dierker
(Formerly Donna Hanlon; no change in marital status -- see 
http://home.att.net/~donna.hanlon for details.)

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