Hi Pedro,

Yes -- Caret does surface-based registration, as described in the registration tutorial:

http://brainmap.wustl.edu/caret/pdf/Caret_5.5_Tutorial_Segment.pdf

If these two surfaces are from the same subject, then the core 6 landmarks (the set typically recommended for inter-subject registration) will not achieve optimal registration; in that case, additional landmarks (e.g., STS, POS -- as many as you can reliably identify across timepoints) are recommended.

For each surface, you'll need to use Surface: Geometry: Generate inflated and ellipsoid from fiducial, to generate inputs the above tutorial expects. You might also consider trying John's new method for registration without flattening:

http://brainmap.wustl.edu/pub/donna/PUBS/Reg_no_flat_and_new_border_drawing.pdf
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I haven't tried it myself yet. I'm not sure whether your Caret version will include all the features you need to try this.

Finally, we tend to use the midthickness (fiducial) surface, rather than the WM/GM surface. We generate a midthickness surface by averaging coordinates of Freesurfer-generated [lr]h.white and [lr]h.pial surfaces.

Donna

On 06/19/2007 04:48 PM, Pedro A. Valdes Hernandez wrote:
Hi:
I' completely new in this mailing list so maybe my question is a little bit foolish I have two triangulated WM/GM surfaces, I'd like to know if I can find corresponding anatomical points between them using CARET/SureFit... Thank you in advance
Pedro
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