I neglected to mention Oliver Lyttelton's OHBM2008 poster, which compared
MNI's CIVET registration with Caret, among other things.  It's not the
thorough study that needs doing, but it does illustrate some of the
trade-offs between sulcal alignment and distortions.  CIVET is much more
like Freesurfer's registration algorithm than Caret is.

http://brainvis.wustl.edu/pub/donna/PUBS/OHBM/2008/Lyttelton_HBM_Poster_TTF_final.ppt
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Donna

> Hi Donald, & Dav,
>
> As far as I know, neither Fischl et. al. nor VE et. al. has taken this
> task on seriously.  I vaguely recall someone from MGH registering for
> Caret a while back with the research goal of comparing registration
> methods. I haven't heard anything since then, and I didn't recognize the
> name.
>
> My instincts for approaching the problem are to get source, Caret
> deformed, and FS deformed coords all on the same mesh, and then compute
> distance from deformed to the source.  (DVE probably would use distortion
> between deformed and source.)  The method that minimizes distance to the
> source (or distortion) wins.  But of course getting all on the same mesh
> requires registration, and you could easily introduce more error than you
> are measuring.
>
> I have read Arno's paper, which is interesting, but it covers volumetric
> algorithms (using Freesurfer in the process, though).  I've shared some
> ideas with Arno for additional analyses he could do with this data, but he
> has plenty on his plate already.  I believe Arno is planning to evaluate
> surface-based methods, but only fully automated ones.  He regularly
> hassles me about whether our auto-landmark algorithm is ready for him to
> try (not yet, but maybe by August?).
>
> One can hypothesize about which method might do better for given
> applications.  But evidence to support those hypotheses is lacking so far.
>
> It's a very important, but tough problem.
>
> Donna
>
>> Arno Klein is engaged in a fairly ambitious project of comparing
>> various registration algorithms.  So, while it's not exactly what
>> you're asking about, I figure it's worth mentioning:
>>
>> http://www.mindboggle.info/
>>
>> Check out the papers link.  He uses hand-labelled data, though, so
>> there may be some differences with your particular needs.
>>
>> Cheers,
>> Dav
>>
>> On Jun 5, 2009, at 11:27 AM, MCLAREN, Donald wrote:
>>
>>> David/Donna/John:
>>>
>>> Have any of you or perhaps Bruce compared the registration
>>> algorithms of CARET and Freesurfer using their segments? If not, is
>>> there a good metric to decide what registration might be better?
>>>
>>> --
>>> Best Regards, Donald McLaren
>>> =====================
>>> D.G. McLaren
>>> University of Wisconsin - Madison
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