I would say delete that portion where the correspondence is shaky.  If a 
portion of the sulcus is present in both and clearly in correspondence, 
leave that portion.  Where in doubt, delete.

On 07/13/2011 09:57 AM, Colin Reveley wrote:
> So, I have to retract this question; looking at a pial surface it 
> seems pretty clear that the image on the right is a sensible fiducial 
> surface for my data. That's just the anatomy.
>
> But the the question becomes: in landmark registration, where a 
> feature is missing in one surface and present in another, is it best 
> to draw a landmark where the sulcus *should* be on the surface where 
> it is absent (as in figure), or just remove that border from both 
> surfaces.
>
> I would have guessed the latter. I suppose one can try both.
>
> On 12 July 2011 20:31, <[email protected] 
> <mailto:[email protected]>> wrote:
>
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>     Today's Topics:
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>       1. segmentation for surf morphometry issue (Colin Reveley)
>
>
>     ---------- Forwarded message ----------
>     From: Colin Reveley <[email protected] <mailto:[email protected]>>
>     To: <[email protected]
>     <mailto:[email protected]>>
>     Date: Tue, 12 Jul 2011 20:10:37 +0100
>     Subject: [caret-users] segmentation for surf morphometry issue
>     Hello - 
>
>     I'm having a segmentation difficulty. The aim is to register F99
>     (macaque) against an individual. The individual was scanned
>     ex-vivo, so it's an MTR image rather than T1. So the contrast is
>     kind of better than T1 and that may, or may not cause issues with
>     surefit. I've tried segmentation many ways. 
>
>     the data is 0.25mm, so it is is downsampled to 0.5mm. there is a
>     bias field but I think it's corrected pretty well (using FAST, in
>     FSL) and the intensities are uniform.
>
>     The MTR image has to be put into the correct orientation for
>     caret, so I register it to a deskulled F99. I've tried 6 parameter
>     (I see no need to scale it) and affine transforms. I transorm at
>     0.25mm (I upsampled the deskulled F99), and then downsample for
>     surefit.
>
>     whatever I try, the result is the same as the figure attached, on
>     the right next to F99.
>
>     I can tolerate most of the differences, but the issue at the
>     rostral end, where there is a fork in the frontal lobe towards the
>     posterior that is simply absent in F99, F6, wisconsin and all
>     macaque literature. It worries me a lot. It seems a lot of
>     variation for macaque.
>
>     In the left hemisphere, this problem is less pronounced, but I'd
>     like to use the right for obvious reasons.
>
>     It seems like this is a difference in gross anatomy. So it's
>     likely wrong.
>
>     when looking at the surefit result, there is quite a bit of gray
>     matter that, it would seem, has no associated white matter, and
>     hence is rejected from the segmentation.
>
>     I think it does have associated white matter (it must do), and the
>     problem is to do with the linear transforms and/or resampling. Or
>     the MTR, just maybe although I doubt it.
>
>     In any case, I'd be grateful if you'd take a look. the region I'm
>     referring too should be clear from the figure. There's a missing
>     sulcus from my brain, and one that shouldn't be there, in the
>     frontal lobe above the temporal tip.
>
>     help appreciated.
>
>     Colin,
>
>     Sackler Centre
>     Sussex
>

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