I confess I don't follow this 100%, but if you are faced with monkey 
segmentation challenges, Colin's recipe might help.


Begin forwarded message:

> From: Colin Reveley <[email protected]>
> Date: November 20, 2011 11:20:16 AM CST
> Subject: homoeomorphic to sphere
> 
> 
> the problem of a minor topological defect (so minor I still don't know where 
> it is) resulting in freesurfer filling in the surfaces to a solid block for 
> the entire occipital lobe (which obviously won't do) has a simple solution.
> 
>  freesurfer is useful in making WM and pial surfaces, and also "freeview" is 
> really nice for looking at surfaces as diagrams in each plane for comparison 
> to e.g.  paxinos atlas, and targeting roi's as volumes for e.g. seeded 
> tractography with ref to a paper. freesurfer is also more manual giving more 
> freedom if you know what you are doing. Which I don't. but I did get a nice 
> WM and pial line.
> 
> If you don't want those things, don't bother probably. Although, the 
> midthickness generated in caret from FS white and pial is more to my liking 
> than surefit (it looks more like F99) , but that is probably because of my 
> data properties (ex-vivo MTR, rather than in-vivo T1).
> 
> To fix:
> 
> adjust once the 3 surfaces (white, pial, mid) are converted/produced and 
> imported to caret (using commands in e.g. recent VE FS-F99 tutorial). Then, 
> you just can use the GUI and select "crossover smoothing" in the surface 
> menu. And they are fixed. I still cannot see the difference before and after 
> to be honest; it's pretty subtle.
> 
> you could, I'm sure, just import the FS "orig" surface (the first go at a 
> white matter surface), fix it, convert back to freesurfer format and 
> circumvent the entire awfulness of FS spherical topology fixing. I spent a 
> long time with that (inflating it more, less etc). no dice.
> 
> in caret, smooth crossovers on the surfaces works wonderfully, only a few 
> thousand edges changed of more than 200,000.
> 
> This has been work. I'm now pleased with what I have, perfectionist that I 
> am. Do contact me, and I'll advise with what ad-hoc knowledge I have.
> 
> generally: avoid mris_sphere -q, mris_fix_topology process for macaque if it 
> doesn't work off the bat. use CARET crossover smoothing.
> 
> Colin, Sackler Centre, Sussex

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