Omega-3 Kills Cancer Cells

<http://www.newsmax.com/health/Omega_3_kills_cancer_cell/2009/04/02/198839.html?utm_medium=RSS>http://www.newsmax.com/health/Omega_3_kills_cancer_cell/2009/04/02/198839.html?utm_medium=RSS
 


Thursday, April 2, 2009 8:22 AM

Docosahexanoic acid (DHA), an omega-3 fatty acid 
found in fish oils, has been shown to reduce the 
size of tumors and enhance the positive effects 
of the chemotherapy drug cisplatin, while limiting its harmful side effects.

The rat experiments, described in BioMed 
Central's open access journal Cell Division, 
support the plethora of health benefits often ascribed to omega-3 acids.

Professor A. M. El-Mowafy led a team of 
researchers from Mansoura University, Egypt, who 
studied DHA's effects on solid tumors growing in 
mice, as well as investigating how this fatty 
acid interacts with cisplatin, a chemotherapy 
drug that is known to cause kidney damage.

"DHA elicited prominent chemopreventive effects 
on its own, and appreciably augmented those of 
cisplatin as well,” El-Mowafy said. “Furthermore, 
this study is the first to reveal that DHA can 
obliterate lethal cisplatin-induced nephrotoxicity and renal tissue injury."

DHA is an omega-3 fatty acid commonly found in 
cold-water fish oil and some vegetable oils. It 
is a major component of brain gray matter and of 
the retina in most mammalian species, and it is 
considered essential for normal neurological and cellular developments.

The researchers found that, at the molecular 
level, DHA acts by reducing leukocytosis (white 
blood cell accumulation), systemic inflammation, 
and oxidative stress ­ all processes that have been linked with tumor growth.

El-Mowafy and his colleagues have called for 
greater deployment of omega-3 in the fight against cancer.

"Our results suggest a new, fruitful drug regimen 
in the management of solid tumors based on 
combining cisplatin, and possibly other 
chemotherapeutics, with DHA,” they write.

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