Postdoctoral Position to study Radiation damage on metal centers and Soft X-rays Studies


Starting date: As soon as possible, after closing date

Job description: BIOXHIT (Biocrystallography on a Highly Integrated Technology Platform for European Structural Genomics) is an integrated project within the EU's 6th Framework Programme. It brings together scientists at all European synchrotrons and leading software developers to produce a highly effective technology platform for Structural Genomics. It aims to consolidate the process of bio-macromolecular structure solution from the bottom up.

The successful applicant will work in a stimulating scientific environment at the Macromolecular crystallography group at the Department of Biomolecular Structural Chemistry, a member of Max F. Perutz Laboratories - University Departments at the Vienna Biocenter, University of Vienna. The Department is equipped to carry out all steps from gene cloning to structural analysis including recently installed Bruker X8 PROTEUM system.  The Group has additionally access to the high throughput nano-drop crystallisation robotics operational at Institute of Molecular Pathology (IMP), based at Campus Vienna Biocenter as well as to major European synchrotron high brilliance X-ray sources.

The selected candidate will focus on two related projects: one will be the investigation of radiation damage on the active centers of selected set of metallo-enzymes and the study effect of free-radical and electron scavengers with the aim to reduce such damage to these metal centers. The other will be the use of soft X-rays in macromolecular crystallography for phasing as well as functional characterization purposes, with the focus on the design of the diffraction experiment.

Qualifications and experience: In addition to a PhD in a relevant area, experience in protein _expression_ and purification and in macromolecular crystallography techniques including crystal growth, data-collection as well as familiarity with standard crystallographic software are required.

Contract: A 2 year contract will be offered to the successful candidate.

Closing date: 15 January 2006

Web pages:

www.bioxhit.org

http://www.mfpl.ac.at/index.php?cid=58

http://www.univie.ac.at/biolchem


Further information can be obtained from Kristina Djinovic Carugo  [EMAIL PROTECTED].

University of Vienna is an equal opportunity employer.

To apply for this position, please email a detailed CV with concise description of research experience and the names and addresses of at least two referees to: [EMAIL PROTECTED], ****AND**** register at the University of Vienna:
http://gerda.univie.ac.at/personal/artikel.php?Sprach_ID=1&Art_ID=668




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Max F. Perutz Laboratories
University Departments at the Vienna Biocenter
Department for Biomolecular Structural Chemistry
Faculty of Chemistry, University of Vienna
Campus Vienna Biocenter 5
A-1030 Vienna
Austria

e-mail: [EMAIL PROTECTED]
Phone: +43-1-4277-52203 
Mobile A: +43 699 10 66 38 56
Fax: +43-1-4277-9522
Home home: + 43 1 208 71 77

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