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Positions open:
Postdoctoral Fellow Research Scientist
Medical Structural Genomics of Pathogenic Protozoa
Biomolecular Structure Center
University of Washington, Seattle
The MSGPP project at the University of Washington is a collaborative
effort involving medical researchers, synthetic and computational
chemists, and crystallographers. Our overall goal is to identify
and exploit potential drug targets drawn from the genomes of eukaryotic
pathogens such as Plasmodia, Trypanosoma, Entamoeba, Giardia,
Cryptosporidia, and Leishmania.
We have immediate openings for postdoctoral fellows and research
scientists to participate as crystallographers. The focus of their
efforts will be
- initial structure determination of selected target proteins
- identification of potential starting points for drug design based
on known inhibitors of homologous proteins
- identification of potential starting points for drug design based
on crystallographic screening of cocktails (mixtures) of chemically
distinct fragments
- collaboration with synthetic and computational chemists to exploit
crystallographically identified binding interactions
Experience with a range of structure determination methods is a plus,
although SeMet MAD phasing is the primary method planned for initial
structure determinations.
Prior experience with crystallographic computing is essential.
Please send CV, list of publications, a description of research
interests and experience, plus a list of three references by Email
to
Ethan Merritt <[EMAIL PROTECTED]>
Biomolecular Structure Center
Department of Biochemistry
University of Washington
Seattle, WA 91895-7742 USA
Related openings:
See also recent announcements of MSGPP positions in
protein crystallization (group of Wim Hol)
and computational chemistry (group of Christophe Verlinde)
