The Protein Crystallography (PX) group of the Structural Genomics
Consortium (SGC) in Toronto
is currently recruiting more crystallographers to extend and expand core
crystallographic expertise of the SGC:
- Research Associate (1)
- Postdoctoral Fellows (1)
For inquiries, please contact:
[EMAIL PROTECTED]
alternatively, keep an eye on our jobs page
http://www.sgc.utoronto.ca/SGC-WebPages/toronto-employment.php
where some other positions are already advertised.
The SGC
===========
The
Structural Genomics Consortium (SGC) is a not-for-profit
organization that aims to determine the three dimensional structures of
proteins of medical relevance, and place them in the public domain without
restriction. The SGC operates out of the Universities of Oxford and Toronto and Karolinska Institutet, Stockholm. The Target List comprises proteins
that have relevance to human health and disease, such as proteins associated
with diabetes, cancer, and infectious diseases such as malaria. Research at the
SGC is divided into three areas: structural genomics of soluble proteins,
structural genomics of integral membrane proteins, and structural chemistry of
soluble proteins. SGC is jointly funded by the Wellcome Trust, a consortium
of Canadian and Swedish funding agencies, and GlaxoSmithKline, and is one of the
largest structural proteomics projects in the world. Operations are split
independently between the universities of Oxford,
Toronto and
Karolinska Institutet but under overall leadership of Aled Edwards, the Chief
Executive. The Toronto
site is housed in the Banting Institute, University of Toronto Faculty of
Medicine, and coordinated by Cheryl Arrowsmith, the Chief Scientist.
The SGC is adopting a biology-centered approach to structural genomics: dedicated
biology groups with target-specific expertise work on getting the proteins
soluble, and biophysical and functional characterizations feature prominently.
The emphasis is decidedly on achieving high per-target success rates rather
than merely high target throughput. Interesting biological questions are
further pursued either in-house or through collaborations.
The PX group
=============
Primary responsibility of the PX group, led by Alexey Bochkarev, goes from
assisting Biology groups in improving crystals to finalized structure, but also
pursuing follow-up structural studies into function and biology, in close
collaboration with the Biology groups of the SGC. It will also actively
work in methodology development, specifically for improving efficiency of SGC
operations, but more generally according to the interests of group members.
For more information see
http://www.sgc.utoronto.ca/SGC-WebPages/sgc-toronto.php
Cheers
Alexey
Alexey Bochkarev, Ph.D.
Principal Investigator, Structural Genomics Consortium
Associate Professor, Banting and Best Dept of Medical
Research & Dept. of Medical Genetic and Microbiology
University of Toronto
http://www.sgc.utoronto.ca/SGC-WebPages/alexey_bochkarev.php
