*** For details on how to be removed from this list visit the *** *** CCP4 home page http://www.ccp4.ac.uk ***
Hi: I am using Ccp4i (v 6.01) and started with a pair of SAD datasets (.sca files from denzo) and then ran the shelxc/d/e suite with them. I got some probably mediocre hits (cc<12%) but decided to use the best atoms from the shelx hits and refine 'em with mlphare -- the sca file I described I ran through scalepack,truncate and cad to get the mtz file to refine against the shelx sites. I have made sure I'm refining anom.occupancy only (Se atoms) but I find the sites and their occupancy are being consistently refined to 0, often within ~8 cycles. Any ideas what I may be doing wrong? Thanks for your help Alex
