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On Mon, 2006-10-30 at 10:15 -0500, S.G. Jackson wrote:
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> 
> Hi, This may be a stupid question however a colleague and I engaged in
> a discussion about this and were looking for a clarification!
> 
> When we set aside some fraction of our data for the Rfree calculations
> we do this by assigning that subset of data a number to distinguish it
> from the data we will use during refinement.  While running various
> refinement programs from ccp4 we tell the programs which number to use
> for identifying data to be used for the Rfree calcs, but when running
> coot we are never given the option to do so (atleast i have not
> encountered this option).  

> Does coot recognize in the input file which
> subset of the data should be excluded or does it use all of the
> data????

It depends on which interface you use to calculate structure factors.
The usual way is running refmac and that will use the Rfree flag if you
have it.

More esoterically (and I doubt that this is what you had in mind), we
have:
(calc-phases-generic file-name); will use the Rfree flag if you have it
(it runs refmac).
(map-from-mtz-calc-phases file-name f sigf imol); will not use the Rfree
flag 

HTH, 

Paul.


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