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Dear all,

I am trying to refine a co-factor that is covalently bound to a cysteine residue in my protein. I've made a dictionary for the co-factor using the Pro-Drug website, but I cannot work out how to define the bond between the co-factor and the sulphur atom of the protein residue. Whenever I google this I just get linked to the refmac page :

http://www.ysbl.york.ac.uk/~garib/refmac/docs/dictionary/link_and_mod.html

which doesn't really tell me what I need to put into the dictionary to define the bond. Could anyone help?

Thanks,

Simon



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