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We are pleased to announce ... NORMA: a tool for flexible fitting of high-resolution protein structures into low-resolution electron-microscopy-derived density maps NORMA is a freely available software suite that allows to model large conformational changes of 3-D protein structures under the constraint of a low resolution electron density map. Typical applications are the interpretation of electron microscopy data using atomic scale resolution structural models. The software package provided here should enable the interested user to perform flexible fitting on new cases without encountering major technical difficulties. It couples Jorge Navaza's fitting programme URO (based on AMoRe principles) with Yves-Henri Sanejouand's normal mode analysis code. NORMA can be downloaded from http://www.elnemo.org/NORMA/ I hope this posting will find your interest. Kind regards, Karsten Suhre. Link: ==== http://www.elnemo.org/NORMA/ Reference: ======== Suhre K, Navaza J, and Sanejouand YH, NORMA: a tool for flexible fitting of high resolution protein structures into low resolution electron microscopy derived density maps, Acta Cryst. D, Vol. 62, pp. 1098-1100, 2006. http://journals.iucr.org/d/issues/2006/09/00/mv5006/mv5006.pdf (open access) PS: === Users of our elNemo normal mode web server might be interested to know that elNemo has migrated to a yet more powerful server and is now accepting even larger jobs with up to four jobs being able to be run in parallel. elNemo now also has a generic web address that is: http://www.elnemo.org
