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any opinions on how pseudo-centering, eg. C2 type in P2(1) etc might affect results in shelxd,e...? i seem to have weak derivatives with low res anom signal, and at low res many times distributions are not random/could be mainly one CC for instance. but phasing produces nothing but gargabe. well perhaps because a) occopancies are too low b) with e.g. KI resolution is too low. (no anom signal beyond 3.5Å+ice and so on) --but i am wondering if the pseudo-symmetry has any effect? thanks for tips/opinions, tommi -- Tommi Kajander, Ph.D. Macromolecular X-ray Crystallography Research Program in Structural Biology and Biophysics Institute of Biotechnology PO box 65 (Street address: Viikinkaari 1, 4th floor) University of Helsinki FIN-00014 Helsinki, Finland Tel. +358-9-191 58903 Fax +358-9-191 59940
