Nian Huang wrote:
Hi, all, I met some crystal structures with disordered active sites. Soaking common ligands can not make it become ordered. I am wondering what people generally do in such situation.Thanks, Nian Huang
Swear?!This is quite common - the usual tricks may work - Sulphate , phosphate may bind there but it depends on your true substrate, and often it takes a clever chemist to make a suitable substrate mimic.
Eleanor
