[ccp4bb] Partial binding of ligand to multimer

[Michal Harel]

Hi all,  We have a structure of a pentamer which was crystallized from 
a complex of the protein with a ligand.  The structure shows that 4 out 
of 5 binding sites are occupied.  The symmetry-related molecules pack 
much tighter around the unoccupied monomer.  I am looking for examples 
of structures in which a ligand was "kicked out" of a binding site upon 
crystallization.

Regards - Michal.
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Dr. Michal Harel
Dept. of Structural Biology          [EMAIL PROTECTED]
Weizmann Inst. of Science                  tel:  972-8-9342647
Rehovot 76100, ISRAEL                      fax:  972-8-9344159
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