Try elbow.builder and phenix.refine in the phenix package.  It will make
your life much easier.


Jae Hyun wrote:
> Dear all,
>
> I have a decavanadate anion in my structure, and want to refine it. For
> that, I got parameter and topology files from HIC-Up website, and used in
> CNS. But, it gave the error message as follows:
>
>  Program version= 1.1 File version= 1.1
>  Torsion Topology>
>  Torsion Topology>         fix group ( &atom_rigid )
>  SELRPN:      0 atoms have been selected out of   4464
>  Torsion Topology>
>  Torsion Topology>       end
>  Torsion Dynamics>       nstep=0
>  Torsion Dynamics>       cmremove=true
>  Torsion Dynamics>     end
>  -------------------------- Torsion Topology
> -----------------------------------
>    ERROR: A group has too many joints.
>           Please increase MAXJNT and re-run.
>
>  %TORSION:TOPOLOGY error encountered: Fatal Topology Error
>    (CNS is in mode: SET ABORT=NORMal END)
>  *****************************************************
>  ABORT mode will terminate program execution.
>  *****************************************************
>  Program will stop immediately.
>
>
> And, I also tried to generate CIF files of the decavanadate so that I can
> use REFMAC. But, it gives other error message like this:
>
>
>   WARNING : DVT      : observed angle value will used
>                   chem_type : OH1 -V   -O      99.322 (O26 -V9  -O8
>   WARNING : DVT      : observed angle value will used
>                   chem_type : O2  -V   -O      79.829 (O4  -V9  -O8
>   WARNING : DVT      : observed angle value will used
>                   chem_type : O2  -V   -O     152.442 (O27 -V9  -O8
>   WARNING : DVT      : observed angle value will used
>                   chem_type : O2  -V   -OH1    99.366 (O23 -V10 -O28
>   WARNING : DVT      : observed angle value will used
>                   chem_type : O2  -V   -O2     78.183 (O23 -V10 -O18
>   WARNING : DVT      : observed angle value will used
>                   chem_type : O2  -V   -O2    154.744 (O23 -V10 -O15
>   WARNING : DVT      : observed angle value will used
>                   chem_type : O2  -V   -O2     75.004 (O23 -V10 -O27
>   WARNING : DVT      : observed angle value will used
>                   chem_type : O2  -V   -O      75.164 (O23 -V10 -O2
>   WARNING : DVT      : observed angle value will used
>                   chem_type : O2  -V   -O2     99.544 (O18 -V10 -O15
>   WARNING : DVT      : observed angle value will used
>                   chem_type : O2  -V   -O2    147.025 (O18 -V10 -O27
>   WARNING : DVT      : observed angle value will used
>                   chem_type : O2  -V   -O2     96.632 (O15 -V10 -O27
>   WARNING : DVT      : observed angle value will used
>                   chem_type : O2  -V   -O      79.049 (O18 -V10 -O2
>   WARNING : DVT      : observed angle value will used
>                   chem_type : O2  -V   -O      79.699 (O15 -V10 -O2
>   WARNING : DVT      : observed angle value will used
>                   chem_type : O2  -V   -O      75.832 (O27 -V10 -O2
>   WARNING : DVT      : observed angle value will used
>                   chem_type : OH1 -V   -O2    102.115 (O28 -V10 -O18
>   WARNING : DVT      : observed angle value will used
>                   chem_type : OH1 -V   -O2    105.654 (O28 -V10 -O15
>   WARNING : DVT      : observed angle value will used
>                   chem_type : OH1 -V   -O2    100.876 (O28 -V10 -O27
>   WARNING : DVT      : observed angle value will used
>                   chem_type : OH1 -V   -O     174.132 (O28 -V10 -O2
>   WARNING: there is not metal chirality for:V10
>   WARNING: there is not metal chirality for:V1
>   WARNING: there is not metal chirality for:V9
>   WARNING: there is not metal chirality for:V7
>   WARNING: there is not metal chirality for:V6
>   WARNING: there is not metal chirality for:V8
>   WARNING: there is not metal chirality for:V5
>   WARNING: there is not metal chirality for:V2
>   WARNING: there is not metal chirality for:V4
>   WARNING: there is not metal chirality for:V3
>  * Plotfile: /tmp/refmac5_temp1.20489_new_DVT.ps
>   --------------------------------
>   --- title of input coord file ---
>
>   PDB_code:xxxx
>   PDB_name:----
>   PDB_date:XX-XXX-XX
>   --------------------------------
>    ... and more ...
>   Number of chains                  :       4
>   Total number of monomers          :     624
>   Number of atoms                   :    4430
>   Number of missing atoms           :      71
>   Number of rebuilt atoms           :       0
>   Number of unknown atoms           :       0
>   Number of deleted atoms           :       0
>
>   Number of bonds restraints    :    4389
>   Number of angles restraints   :    6074
>   Number of torsions restraints :    3037
>   Number of chiralities         :     638
>   Number of planar groups       :     763
>   I am writing new library:
>   /ccp4/P
>
> Important, Important, Important!!!!!
>
> Your coordinate file has a ligand which has either minimum or no
> description
> in the library
> A new ligand description has been added to /ccp4/PROJECT_6_lib.cif
> Picture of the new ligand can be viewed using postscript file. See above
> Check description in this file and, if satisfied, use it as the input
> library
> Otherwise either edit bond orders manually or use CCP4i Sketcher to view
> and
> edit the ligand
> and create a library entry by running libcheck
> It is strongly recommended that dictionary  entry should be checked
> carefully before using it
> If you are happy with the library description then use the keyword (MAKE
> CHECK NONE)
> I.e. do not check correctness of the coordinates
> ===> Error: New ligand has been encountered. Stopping now
> <B><FONT COLOR="#FF0000"><!--SUMMARY_BEGIN-->
>  Refmac_5.2.0019:  New ligand has been encountered. Stopping now
> Times: User:       7.7s System:    0.2s Elapsed:     0:08
> </pre>
> </html>
> <!--SUMMARY_END--></FONT></B>
>
>
> I need your kind advice to solve this problem. Thank you in adveance.
>

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