Postdoctoral associate in RNA Structural Biochemistry
Introduction:
The Department of Cell and Molecular biology (CMB) at the Karolinska
Institutet in Stockholm is strongly focused on basic science
conducting research in several areas of cell, molecular, and
developmental biology. CMB is comprised of more than 20 independent
research groups organized in five themes: Molecular Cell Biology,
Developmental and Stem Cell Biology, Gene Regulation, Genome
Structure and Integrity and Infection and Cancer. The group of Martin
Hallberg - belonging to the theme of Molecular Cell Biology - apply X-
ray crystallography, electron microscopy and biochemistry to
understand tRNA processing, modification and transport.
Research description:
Transfer RNAs (tRNAs) must be recognised by the correct aminoacyl-
tRNA synthase, by elongation factors and by elements on the ribosome
to deliver their valued amino-acid cargo to the growing peptide chain
through the action of the ribosome. In all kingdoms of life,
mechanisms are in place to ensure the fidelity and efficiency of tRNA
function. We aim to understand the structural basis of tRNA
maturation and transport by studying the molecular structure of
proteins - both with and without target RNA – that are involved in
processing, modification and nucle-cytoplasmatic transport of tRNA.
Successful candidates will participate in all steps involved in
structure determination of target proteins and target RNA/protein
complexes.
Suitable candidates have a PhD in a relevant area, preferably in RNA
Biochemistry, Structural Biology or closely related subjects. A
general requirement to be eligible for this position is a doctoral
degree from a University outside Sweden.
The position is offered for two years (full-time) and is funded by a
non-taxable scholarship.
Last date for applications is July 18 (2007). Please, use reference
“Dnr 2966/2007”.
The application should contain a cover letter and a CV with
publication list. Names and emails of two references should be also
provided.
Application sent to:
Att: Martin Hallberg Dnr 2966/2007
CMB
Medical Nobel Institute
Karolinska Institutet
Box 285
171 77 Stockholm
Sweden
or through email: [EMAIL PROTECTED]
Please see: http://jobb.ki.se/external/ad/showAd.asp?adId=1285
.
B. Martin Hallberg, PhD
Assistant professor
Department of Cell and Molecular Biology
Medical Nobel Institute
Karolinska Institutet
Nobels väg 3 (visiting address)
SE-171 77 Stockholm
Sweden
