We've had a case recently (unpublished) with 4 molecules in the asymmetric unit, two self-contained and two domain-swapped (asymmetrically)

... anything is possible, though in this case the "domains" are really separate proteins expressed as an artificial fusion

Phil


On 5 Oct 2007, at 15:40, Miriam-Rose Ash wrote:

Hey all,

Sorry for the off-topic post, but I'm just wondering if anyone has heard of any examples in which a single crystal contained both the domain-swapped and unswapped forms of a protein?

Thanks!
Miriam

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