Hello Everyone,
   
  I have a question about how to improve the electron density. I have two 
indepedent molecules in the asymmetric unit (1.9 A resolution). I solved the 
structure with PHASER and refined with CCP4i (Rfree = 0.29). 
   
  For the first molecule, the density is very good, but for the second one, the 
density is much worse than the first one. Are there any ways to improve the 
density of the second molecule, such as some kinds of averaging? Why that 
happens?
   
  Thank you very much for your help!
   
  Sincerely,
   
  Sun Tang
  [EMAIL PROTECTED] 

       
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