Hi Neeraj,
a couple of S100 proteins bind Zn2+ and Ca2+. Ca2+ binds to EF-hands;
Zn2+ binds to specific sites distinct of the EF-hands. We are
investigating Zn2+-binding by spectroscopy and crystallography. We think
that Zn2+ is like Ca2+ a kind of second messenger. If you have
questions, I am happy to discuss these things.
Best,
Guenter
Hi all,
I recently came across a question about an interesting idea.
Does anyone know of an example of a protein binding to both Zn2+ and
Ca2+ at the same time? Are there any known well studied precedents at
all if any. Any help of insights would be very valuable.
thanks,
Neeraj
--
***********************************
Priv.Doz.Dr. Guenter Fritz
Fachbereich Biologie
Sektion Naturwissenschaften
Universitaet Konstanz
http://www.biologie.uni-konstanz.de/fritz
Universitaetsstrasse 10
Postfach M665
D-78457 Konstanz
e-mail: [EMAIL PROTECTED]
Tel. Office: +49-(0)7531 88 3205
Tel. Lab : +49-(0)7531 88 3687
Fax: +49-(0)7531 88 2966
