Hi there. Clostridial Alpha toxins (phospholipase Cs that cause gas gangrene) bind 2-3x Zinc in the catalytic site, and 2-3 Ca in the membrane binding domain. See 1ca1, 1olp, 1qmd and others.
Dave 2008/6/13 Neeraj Kapoor <[EMAIL PROTECTED]>: > Hi all, > I recently came across a question about an interesting idea. Does > anyone know of an example of a protein binding to both Zn2+ and Ca2+ at the > same time? Are there any known well studied precedents at all if any. Any > help of insights would be very valuable. > > thanks, > Neeraj > -- ============================ David C. Briggs PhD Father & Crystallographer http://www.dbriggs.talktalk.net AIM ID: dbassophile ============================
