Hi,
Can anyone advise me what is currently the weakest protein-protein
complex yet crystallised? Google searching turned up a paper from the
Tromsø crystallography group (Helland et al. 1999, JMB 287, 923–942)
in which a complex between beta-trypsin and a P1 mutant of BPTI with a
Kd of 68 uM was described as belonging to the weakest complexes solved
to date, but this article was from 1999 and much water has passed
under the bridge since then.
Thanks
Derek
_________________________________________________________________
Derek Logan tel: +46 46 222 1443
Associate professor fax: +46 46 222 4692
Molecular Biophysics mob: +46 76 8585 707
Centre for Molecular Protein Science
Lund University, Box 124, 221 00 Lund, Sweden
