Hi Bernhard, Google books is your friend... It returns 2 hits for "Although the hydrogen bond is not strong it has great significance in determining the properties of substances. Because of its small bond energy"
Both are essays / chapters by Max Perutz I Wish I'd Made You Angry Earlier: Essays on Science, Scientists, and Humanity - Page 166 has the quote attributed to Pauling but without reference. http://books.google.com/books?id=GkODMkCWndQC&pg=PA166&dq=%22Although+the+hydrogen+bond+is+not+strong+it+has+great+significance+in+determining+the+properties+of+substances.+Because+of+its+small+bond+energy%22&sig=ACfU3U0HC6n1toHJgD9Z-bedRSs7eVvz8Q And Pioneering Ideas for the Physical and Chemical Sciences: Josef Loschmidt's ... - Page 1 by W. Fleischhacker, Thomas Schönfeld has a chapter titled "The significance of the hydrogen bond for physiology" by Max Perutz where the quote is attributed to being from Pauling's "newly published Nature of the Chemical Bond" which Perutz obtained with a Christmas 1939 "book token" so I presume it was the 1940 version. http://books.google.com/books?id=cMc9BHNyIWsC&pg=PA1&lpg=PA1&dq=%22Although+the+hydrogen+bond+is+not+strong+it+has+great+significance+in+determining+the+properties+of+substances.+Because+of+its+small+bond+energy%22&source=web&ots=sU9k_3dU9w&sig=3ZCCE8u8ZpLBa-ycU2v0eT1s4og&hl=en&sa=X&oi=book_result&resnum=2&ct=result The 1960 version of Pauling's book is on Google books and it has a similar but not identical statement. see pp. 449-450. http://books.google.com/books?id=L-1K9HmKmUUC&printsec=titlepage&dq=Nature+of+the+Chemical+Bond+Pauling&source=gbs_toc_s&cad=1#PPA449,M1 Regards, Mitch -----Original Message----- From: CCP4 bulletin board [mailto:[EMAIL PROTECTED] On Behalf Of Bernhard Rupp Sent: Wednesday, July 23, 2008 10:26 PM To: [email protected] Subject: [ccp4bb] quote source Dear All, does someone know the proper reference of this L. Pauling statement? "Although the hydrogen bond is not strong it has great significance in determining the properties of substances. Because of its small bond energy and the small activation energy involved in its formation and rupture, the hydrogen bond is especially suited to play a part in reactions occurring at normal temperatures. It has been recognised that hydrogen bonds restrain protein molecules to their native configurations, and I believe that as the methods of structural chemistry are further applied to physiological problems it will be found that the significance of the hydrogen bond for physiology is greater than that of any other single structural feature". It is quoted by Perutz but no ref Thx, br ----------------------------------------------------------------- Bernhard Rupp 001 (925) 209-7429 +43 (676) 571-0536 [EMAIL PROTECTED] [EMAIL PROTECTED] http://www.ruppweb.org/ ----------------------------------------------------------------- The hard part about playing chicken is to know when to flinch -----------------------------------------------------------------
