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http://tinyurl.com/linusp On Jul 23, 2008, at 10:26 PM, Bernhard Rupp wrote:
"Although the hydrogen bond is not strong it has great significance indetermining the properties of substances. Because of its small bond energy and the small activation energy involved in its formation and rupture, the hydrogen bond is especially suited to play a part in reactions occurring at normal temperatures. It has been recognised that hydrogen bonds restrain protein molecules to their native configurations, and I believe that as themethods of structural chemistry are further applied to physiologicalproblems it will be found that the significance of the hydrogen bond for physiology is greater than that of any other single structural feature".
