Postdoctoral Position in Protein Crystallography at the Beatson Institute for Cancer Research, Glasgow
We are seeking an experienced postdoctoral researcher to investigate the structure of cancer related proteins and drug targets. We are a newly established group at the Beatson Institute for Cancer Research in Glasgow, UK. Our group is interested in the kinesin superfamily with a focus on human mitotic kinesins and their associated proteins. Many of these proteins are good targets for drug development in cancer chemotherapy. In addition, we collaborate with other groups at the Institute to determine the structures of cancer-related proteins. We have a well-equipped state-of-the-art laboratory for all aspects of structural work including ÄKTA protein purification systems, a Mosquito nano-drop robot for protein crystallisation, an automated storage and visualisation system (Formulatrix), and a Rigaku HighFlux Homelab microfocus diffraction system. In addition, we are well equipped to characterise the biochemistry of protein - inhibitor complexes towards the optimisation of lead compounds in collaboration with our chemistry colleagues. The Beatson Institute has a large range of core service facilities including DNA sequencing, protein production (E. coli and Baculovirus) and mass spectrometry. Applicants must hold a PhD in structural biology with a strong background in protein crystallography. Experience in protein expression, purification and the determination of x-ray crystal structures of proteins would be strongly favoured. The position is available for 3 years with the possibility of an extension for a further 2 years. Closure date: 31-10-2008 Applications for the above post with CV and names of three referees should be send by email to: Prof. Frank Kozielski The Beatson Institute for Cancer Research Switchback Road, Bearsden Glasgow G61 1BD Scotland Email: [EMAIL PROTECTED] http://www.beatson.gla.ac.uk/Regulation-of-Cancer-Cell-Proliferation-and-Growth/Frank-Kozielski-Molecular-Motors.html
