Hi Priya, you may try this as well, available as both a web server and a standalone application. http://geometry.molmovdb.org/3v/ Regards, Roberto
--- Roberto T. Bossi tel.: +39 0331 58 1914 fax.: +39 0331 58 1360 E-Mail: [EMAIL PROTECTED] Structural Chemistry Department of Chemistry NERVIANO MEDICAL SCIENCES Viale Pasteur 10 20014 Nerviano (MI) - Italy Web: www.nervianoms.com ******************************************** ________________________________ From: CCP4 bulletin board [mailto:[EMAIL PROTECTED] On Behalf Of Hector H Hernandez Sent: Monday, November 10, 2008 4:31 PM To: [email protected] Subject: Re: [ccp4bb] Channel inside a protein Hello Priya, Here is a great example of the identification of a channel in a protein. The authors used CAVENV to identify the channel and confirmed the channel by solving the structure of Xenon-pressured crystals. Hector Xenon in and at the End of the Tunnel of Bifunctional Carbon Monoxide Dehydrogenase/Acetyl-CoA Synthase Tzanko I. Doukov, Leah C. Blasiak, Javier Seravalli, Stephen W. Ragsdale, and Catherine L. Drennan http://pubs.acs.org/cgi-bin/abstract.cgi/bichaw/2008/47/i11/abs/bi702386 t.html Hector H Hernandez, PhD Massachusetts Institute of Technology Civil and Environmental Engineering Postdoctoral Associate [EMAIL PROTECTED] On Nov 10, 2008, at 10:21 AM, hari jayaram wrote: Hi Priya , I would recommend MOLE from the list kindly compiled by "Jiamudu" on the CCP4 wiki The list is available at the link below <http://strucbio.biologie.uni-konstanz.de/ccp4wiki/index.php/Programs_fo r_representing_the_surface_of_a_channel_inside_protein> http://strucbio.biologie.uni-konstanz.de/ccp4wiki/index.php/Programs_for _representing_the_surface_of_a_channel_inside_protein Hari On Mon, Nov 10, 2008 at 9:16 AM, Priya Mudgal <[EMAIL PROTECTED]> wrote: Hello All, Is there any program that can find if there is a channel inside a protein? I also would like to know what are the alternative ways to find out a channel inside a protein. Thanks a lot. Priya
