Hi David:

I haven't read all my email yet so apologize if this has already been mentioned, but Fred Allain and Gabriele Varani did something along these lines specifically for nucleic acids (RNA):

F.H.T. Allain and G. Varani. How Accurately and Precisely can RNA Structure be determined by NMR? J. Mol. Biol. 267 338-351 (1997)

HTH,

Bill



On Nov 13, 2008, at 8:57 PM, David Chenoweth wrote:

Dear all,

Does anyone know of a good published reference that describes the pros and cons of X-ray versus NMR structure determination. Something specific to nucleic acids would even be better. I've noticed that several papers describe NMR structures as "atomic resolution structures" and I'm just wondering what people think of this.

Thanks in advance,
David

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David M. Chenoweth
California Institute of Technology
Division of Chemistry and Chemical Engineering
Mail Code: 164-30
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California, USA

Phone: 626-395-6074
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