Applications are invited for a postdoctoral position to work on the
structure determination of membrane transport proteins critical in
cardiovascular function. The transporters we study have been linked to
human disorders such as cardiomyopathy, ischemia-reperfusion injury,
and various cancers. Our aim is to understand the molecular regulation
of the transporters with the goal of rational design of novel
inhibitors and activators. We seek an enthusiastic candidate
experienced in macromolecular x-ray or electron crystallography.
Experience with membrane protein biochemistry would be an asset. In
addition, the successful candidate should be well-versed in one or
more of the following areas: molecular biology, protein purification,
crystallization, and membrane protein and lipid biochemistry.
This is an opportunity to join a lab experienced in the expression and
crystallization of membrane proteins [See Biophysical Journal (2006)
90:4213-23, JBC (2007) 282:9748-57, and JBC (2008) 283:4145-54]. Our
department provides interaction with numerous structural biologists.
In addition, the University of Alberta Membrane Protein Research Group
provides a dedicated forum for membrane protein research that includes
14 research laboratories (http://www.mprg.med.ualberta.ca/index.php ).
The University of Alberta, located in Edmonton, Alberta (Canada), is
home to a large and interactive community of biomedical scientists
http://www.med.ualberta.ca/; support and facilities for structural
biology are excellent. A state-of-the-art facility is available for
electron microscopy at the National Institute for Nanotechnology,
University of Alberta
(http://nint-innt.nrc-cnrc.gc.ca/research/micro/index_e.html), and a
newly commissioned synchrotron facility is located a short drive away.
Edmonton, having a population of approximately 1 million, offers a
cosmopolitan environment with world class performing arts, sports,
culinary and recreational opportunities. In addition, the citys
proximity to the Rocky Mountains including the towns of Jasper and
Banff is an additional bonus.
Salary is commensurate with training and experience at the CIHR
standard rates. A medical and dental benefit package is included with
salary. Funding is also available through several competitive funding
agencies, including CIHR (http://www.cihr.ca/ ) and Alberta Heritage
Foundation for Medical Research (http://www.ahfmr.ab.ca/ ). The
University of Alberta hires on the basis of merit. We are committed to
the principle of equity in employment. We welcome diversity and
encourage applications from all qualified women and men, including
persons with disabilities, members of visible minorities, and
Aboriginal persons. The records arising from this competition will be
managed in accordance with provisions of the Alberta Freedom of
Information and Protection of Privacy Act (FOIPP).
Please direct CV's or inquiries to the following email address:
[email protected].
Howard S. Young
Associate Professor
Department of Biochemistry
University of Alberta
Medical Science Bldg, room 327
Edmonton, AB, Canada
T6G 2H7
National Institute for Nanotechnology,
National Research Council of Canada
Membrane Protein Research Group
(http://www.mprg.med.ualberta.ca/group-members.php)
